Depression directly affects the mental stability of the affected person since it is a form of mental illness. Some of the conditions which depression can lead to in later stage of life are: 

1. Once affected by depression people start losing pleasure in normal activities, they suffer depressed feeling for most of the day.

2. Loss of appetite, weight disturbance, irritation while sleeping, and loss of energy from the body are the after effects of depression.

3. Some other conditions are feeling of suicide, abnormal fatigue for whole day.

4. If the depression persists for long time then it will result in chronic conditions.

5. Depression will lead to poor health and it is found that after conditions of depression are more severe as compared arthritis, asthma and diabetes.

6. Depression can also result in severe back pain and pain in neck.

7. Depression will make the affected person feel that there is nothing left for him in the world, no one cares for him and he considers himself as waste. Due to such thoughts the person also gets feeling of suicide. Most of the suicide cases in the world are due to severe depression.